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Published 07:27 30 Jan 2015 GMT
Updated 18:39 30 Jan 2015 GMT
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O'Brien does not have to look beyond the Ireland captain, Paul O'Connell, for inspiration when it comes to returning to top form after a lengthy injury lay-off. The Munster lock faced a career-threatening back injury in 2012 but returned to star for province, country and the Lions, the following year.
O'Brien says, 'Paulie is the type of player that you look up to, listen to and learn a lot from. Everybody in the squad respects him for the legend he is. He has such a positive manner about him and is still playing at the highest level... even though he's an old man.'
If O'Brien can hit, and possibly surpass, his markers this weekend, he could be in line to start alongside O'Connell for the first time since the New Zealand clash in November 2013. 'We can't look beyond that Italy game as it will be an extremely tough start. It's always a cracker, going over there to play them, their team is getting stronger and they'll throw everything into the first game of the championship.'
*O’Brien teamed up with Guinness, partner of Irish Rugby and Six Nations, to announce 'extraordinary rugby experiences' for rugby fans, available through the Guinness Plus App. Fans who check-in to the pub from now up until the March 22 will be in with a chance to 'Follow in the Team’s Footsteps' by winning a VIP trip for them and two friends to Ireland’s away games against Wales and England this summer. The app (for over 18's) is available to download for iPhone and Android Smartphones from the iTunes App and Google Play Stores. 
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